Adhering to CLSI M22-A3 offers significant operational and regulatory advantages:
Published in June 2004, M22-A3 establishes the quality assurance procedures required for both manufacturers and users of prepared microbiological culture media. Its core premise is that if a medium has a proven track record of reliability, the end-user (the lab) does not need to perform exhaustive retesting. Key Features of the Standard Commercially Prepared "CLSI-Exempt" Media IQCP Example clsi m22a3 pdf link
Standard media with historically low failure rates (e.g., MacConkey agar, Sheep Blood agar, Nutrient agar). Laboratories do not need to perform full organism testing on these lots if the manufacturer provides a valid QC certificate. Adhering to CLSI M22-A3 offers significant operational and
The foundation of M22-A3 is the premise that routine retesting of commercially prepared microbiological culture media by the end user is for media that demonstrate proven reliability. The standard categorizes media into two main groups: Laboratories do not need to perform full organism
Providing a clear QC certificate detailing the organism strains used and the results. 2. User (Laboratory) Responsibilities
The primary goal of M22-A3 is to streamline QC testing by separating media into two distinct categories: