Before altering any software settings, ensure your physical setup allows the Wii hardware to detect your drive. The Wii is notoriously strict about hardware configurations. Port Selection
If you must use a flash drive:
The absolute best format for maximum compatibility across Wii Homebrew, Nintendont (for GameCube), and USB Loader GX. Ensure the cluster size is set to 32KB . wii usb loader gx usb device not initialized repack