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Check your laboratory's purchasing records for the original invoice from Thermo Fisher Scientific or Fisher Scientific.

Primer Express is a specialized bioinformatics tool designed for:

I should start by acknowledging that the software is proprietary and owned by Thermo Fisher Scientific (after the Applied Biosystems acquisition). Then, explain the legal way to obtain a license, maybe through purchasing or academic licenses if they're eligible. Also, highlight the consequences of piracy and why it's important to use legal means.

If you cannot afford Primer Express 3.0.1, several excellent free tools exist for qPCR primer and probe design.