Binds with high affinity to Fc receptors on mast cells and basophils. Cross-linking of IgE by allergens triggers degranulation, driving Type I hypersensitivity and defending against helminthic (parasitic) infections.
Exogenous extracellular antigens (e.g., phagocytosed bacteria) immunology notes dr najeeb lectures pdf new
This consists of over 20 liver-produced proteins that circulate in the blood as inactive "pro-enzymes". Once triggered, they poke holes in bacteria or coat them to make them "tastier" for macrophages (opsonization). Act II: Calling in the Elite Units (Adaptive Immunity) Binds with high affinity to Fc receptors on
Found primarily on the surface of mature, naive B cells, serving alongside IgM as an antigen receptor. 6. Hypersensitivity Reactions naive B cells